Effects of Ulva lactuca mixed with Spirulina platensis on Creatinine and Ureum Levels in Central Obesity Patients

Abstract

Background: Obesity is rising rapidly and is expected to reach 40% by 2030, meaning nearly one in two adults will be obese. Nationally, the prevalence of central obesity has increased significantly, from 18.8% in 2007 to 26.6% in recent years. This study aims to determine the effect Ulva lactuca mixed with Spirulina platensis on creatinine and ureum levels in central obesity patients. Materials and Methods: Its study was a quasi-experimental design with a pretest-posttest control group. This research was carried out in two locations, Soppeng and Makassar, respectively, for intervention and control groups. Subjects were central obese with BMI over 25. One group received simple education and nori 3 g three times a day for 12 days (IG, n=20), while another only received simple education (CG, n=20). To evaluate the variance between groups, a paired t-test and an independent t-test have been used. Results: showed that most subjects were women (87.5 %) and home wives (67.5%). After the intervention, creatinine serum decreased in IG groups (0.889 mg/dL to 0.783 mg/dL, p<0.05 for IG and 0.807 mg/dL to 0.836 mg/dL, p=0.083 for CG). In addition, changes between groups were significant (0.106 mg/dL vs. 0.030 mg/dL, p<0.05). Similarly, ureum serum decreased in IG groups after interventions (50.770 mg/dL to 42.485 mg/dL, p<0.05 for IG and 48.600 mg/dL to 50.200 mg/dL, p=0.247 for CG). Changes between groups were also significant (8.285 mg/dL vs. 1.600 mg/dL, p<0.05). Conclusion: Ulva lactuca mixed with Spirulina platensis are 3 g three times a day for 12 days could decrease creatinine and ureum levels in central obesity patients.